2007年7月24日 星期二

Hypersensitivity

Type 1 - immediate (or atopic, or anaphylactic)

Atopic dermatitis (eczema) (常考)
Allergic conjunctivitis (常考)
Allergic asthma
Allergic rhinitis ("hay fever")
Anaphylaxis
Angioedema
Urticaria (hives)


Type 2 - antibody-dependent (Cytotoxic antibodies)

Pemphigus(常考!)
Cicatricial pemphigoid(常考!)
Autoimmune hemolytic anemia
Immune thrombocytopenia
Transfusion reactions
Hashimoto's thyroiditis
Graves' disease (see type V below)
Myasthenia gravis (see type V below)
Rheumatic fever
Wegner granulomatosis (常考)


Type 3 - immune complex reactions

Scleritis(常考!)
Rheumatoid arthritis
MAR, CAR(重要!)
Phacoantigenic endophthalmitis(重要!)
Steven-Johnson syndrome(重要!)
SLE 的retinal vasculitis(Arthus reaction)


Type 4 - cell-mediated (Delayed-Type Hypersensitivity, DTH)

Phlyctenulosis → 對S. aureus cell wall的過敏反應 (常考)
Contact dermatitis (poison ivy rash, for example)
Temporal arteritis
Symptoms of leprosy
Symptoms of tuberculosis
Transplant rejection : GVHD
Sympathetic ophthalmia (SO), VKH
Interstitial keratitis (IK)


Type 5 – simulatory (type 2 的variant)

Graves' disease
Myasthenia gravis
Wegner granulomatosis



提示:不要只背type多少的數字,考試時也許會用後面的英文名字來混淆。

口訣:

Type 1: atopic, anaphylatic, A開頭,代表第一個,所以是type 1
Type 2:cytotoxic (文字裡有to,就是type two,另外字裡有兩個T,兩個O,也代表type 2)
Type 3:immune-complex(字裡有三個m,所以是type3)
Type 4: (T-)cell-mediated。cell四個字母,所以是type 4

2 則留言:

  1. Type IV 有分 DH1, DH2

    DH2 與 parasite, atopic disease 有關 ex: Toxocara granuloma, Mooren(Mooren 不太確定), VKC裡有提到 Type I and IV (其中的IV 應該就是指 Cooms IV 的 DH2,我猜的)

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  2. Type IV 有2 types
    Th1 DH: SO
    Th2 DH: Toxocara granuloma

    eyedoctorli@yahoo.com.tw

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