HLA

animal的WBC表面有glycoprotein叫MHC
而人類叫HLA (human leukocyte antigen）
有六種：
class Ⅰ：HLA-A,B,C
class Ⅱ：HLA-DR,DP,DQ

HLA gene在Chromosome 6

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HLA B27

比例：

正常population： 5%
A.S→HLA-B27(+) 佔 90%
Reiter syndrome 85~95%
Anterior uveitis→在台灣, HLA-B27(+) 佔 70%
Inflammatory bowel disease→ HLA-B27(+) 不到50%
IBD+scarolitis: 20%

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Behcet disease→HLA B51

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Sarcoidosis→HLA B8,B13

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SO, VKH→HLA DR4
JRA→HLA DR4,Dw2

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Birdshot → HLA A29

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retinal vasculitis→HLA B44

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MS, OHS→ HLA B7, DR2

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intermediate uvetiis→HLA B8,B51