網膜虹睫表神經; 外肌外鞏血內皮。
水晶表角結膜淚; 其它都在神經脊。
七言絕句: 好詩!
外胚層 (Ectoderm)
表面外胚層 (Surface ectoderm)
Lens
Corneal epithelium
Cojunctiva
lacrimal glands cells
視經外胚層 (Neuroectoderm )
optic nerve
Retina (RPE and neurosensory retina)
ciliary epithelium (pigmented and nonpigmented)
Iris muscle : sphincter and dilator
Iris epithelium
神經外胚層–由後往前:
optic nerve→retina→ciliary epithelium→iris muscle+epithelium
神經脊( Neural crest)
sclera(teporal之外的大部份)
choroid
stroma of iris
corneal stroma+endothelium
trabecular meshwork
Ciliary muscle
=> cornea,iris,choroid,stroma都在neural crest!
* 中胚層 (Mesoderm)
構成:
眼外肌的muscle fiber (sheath與tendon屬於neural crest)
sclera的temporal portion (sclera的其它部份由neural crest構成)
眼部血管的endothelial lining
器官整理:
* cornea
epithelium – surface ectoderm
stroma and endothelium – neurocrest
* sclera
temporal portion–mesoderm
其它部份–neural crest
* optic nerve:neuroectoderm
* extraocular muscle
belly – mesoderm
tendon and sheath – neural crest
Uvea
* Iris
Iris muscle (dilator/sphincter)/epithelium – neuroectoderm
Iris stroma–neural crest
* Choroid – neural crest
* Ciliary muscle – neural crest
Melanocyte – neural crest
Trabecular meshwork – Neural crest
* Lens – surface ectoderm
* vitreous–mesoderm + surface ectoderm + neuroectoderm (只差沒有neural crest→因為vitreous沒有 stroma)
* Retina–neuroectoderm
* RPE–neuroectoderm
Anterior chambers 的形成是經由Neural crest cells migrate分化而來
第1波:形成corneal endothelium(1內)
第2波:形成iris, 部份papillary membrane(2彩)
第3波:形成Keratocytes(3角)
口訣: 跳土風舞:「前一二三…向內踩腳」… 1內,2彩,3角
lens embryology:
22天–optic primordium
25天–optic vesicle
27天–lens plate
29天–lens pit
33天–lens vesicle且同時optic vesicle →2 layered optic cup
40天–來至後方的cells elongated→primary lens fiber(embryonic nucleus)→7週至8個月→來至equator的epithelium分化成secondary lens fiber→fetus nucleus
suture–由於lens由外向內分泌fiber,當前後cells相會時,則形成suture,在8週時可見到前有正立Y,後有倒Y結構(前正後倒)
Tunical vasculosa lentis – 分成:
Ant. vascular capsule
來自long ciliary a.
形成pupillary strand
Capsulopupillary portion
Post. vascular capsule
來自hyaloid a.
形成Mittendorf dot
zonular fiber在3個月大時由ciliary epithelium來
congenital aphakia – 分primary (根本沒發育)及secondary(發育後又absorb掉)
* Mesenchymal structures of the head, including the eye, are all derived from "a combination of neural crest cells and mesoderm"
* The mesoderm gives rise to all vascular endothelia, all extraocular muscles, and temporal sclera