原本描述之Triad乃在
1. 上呼吸道之necrotizing granulomatous vasculitis
2. 下呼吸道之necrotizing granulomatous vasculitis
3. focal segmental glomerulonerphitis
* Paranasal sinus (90%), pulmonary, and renal disease （在小血管上的疾病）
* ANCA(+)
* Type 2 hypersensitivity (也列於Type 5)
Ocular complications:
* scleritis with or without peripheral keratitis
* orbital pseudotumors
* vasculitis-mediated retinal vasculitis
治療： prednisone, cyclophosphamide
=> cyclophosphamide在痊癒後再使用一年，之後再tapper off
=> cyclophosphamide的副作用包括：leukopenia, hemorrhagic cyctis, gonadal dysfunction, alopecia, neoplasia
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